By Dongfeng Tan MD, Gregory Lauwers MD
Advances in Surgical Pathology: Gastric Cancer presents a concise, up-to-date assessment of the pathological features of gastric melanoma, with an emphasis on exploring sensible matters and up to date advancements. The ebook beneficial properties present and rising recommendations within the box of gastric melanoma, a illness whose administration calls for a multidisciplinary method within which pathology performs a key position. Its six sections hide the fundamental histopathology of gastric melanoma in addition to similar issues akin to imaging review, molecular analysis, and custom-made therapy, between different components of curiosity. person chapters written by means of foreign specialists within the fields of pathology, gastrointestinal scientific oncology, melanoma epidemiology, and gastrointestinal radiology, deal with the elemental concerns surrounding gastric melanoma, together with its epidemiology, simple diagnostic good points, differential diagnoses, pitfalls and issues, and coverings. Endoscopic assessment and histology correlation are emphasised. The screening, scientific administration, and remedy of gastric melanoma are summarized in similar publication sections. contemporary findings in regards to the roles of immunohistochemistry and molecular trying out within the prognosis, analysis, and customized remedy of gastric melanoma also are reviewed. The ebook additionally contains present wisdom in regards to the molecular alteration of gastric melanoma carcinogenesis and its effect on sufferer care.
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Extra resources for Advances in Surgical Pathology: Gastric Cancer
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2003;95:1784–1791. 3 Helicobacter pylori and Gastric Neoplasms Antonia R. Sepulveda Abha Goyal INTRODUCTION Helicobacter pylori, a Gram-negative bacterium, is the most important human pathogen of the Helicobacter genus. Studies by Warren and Marshal1 were the first to implicate H. pylori as the causative agent of chronic gastritis and ulcers. This discovery led to the Nobel Prize for Medicine and Physiology in 2005. H. 2–4 In this chapter, we review the evidence supporting a role for H. pylori in gastric carcinogenesis, the stepwise pathologic changes of the gastric mucosa (gastritis, gastric atrophy, intestinal metaplasia, and dysplasia/adenoma) that underlie gastric cancer, the role of Helicobacter virulence factors in gastric cancer risk, the molecular mechanisms underlying H.